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Scientific Opinion on the substantiation of a health claim related to vitamin D and contribution to the normal function of the immune system pursuant to Article 14 of Regulation (EC) No 1924/2006 EFSA
- “Vitamin D contributes to the normal function of the immune system”. The target population is children from 3 to 18 years of age.
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See also VitaminDWiki
- Vitamin D: not just bone, but also immunity – July 2016
- Influenza prevented by 40 ng levels or treated with vitamin D hammer (50,000 IU) – June 2015
The VitaminDWiki items in Immunity and Infant-Child are:
- Pfizer COVID vaccinations resulted in altering immune systems (increased IgG4 ) – Aug 2024
- Infections in children reduced a bit by 2,000 IU of vitamin D - meta-analysis July 2023
- Malaria death 3X less likely in mice given vitamin D (looks good for humans too) – meta-analysis June 2023
- 2.4 X fewer lower respiratory track infections in infants getting 400 IU of Vitamin D – May 2022
- Infant and child immunity depends on Vitamin D and two Vitamin D genes – Review April 2020
- Lower Respiratory Tract Infection in Infants reduced 5.9 X by daily 600 IU of vitamin D (China) - March 2020
- I have a PhD in immunology and this is how I keep my daughter from getting sick during the winter
- Preemie immunity (Treg) vastly improved by 800 IU of Vitamin D daily – RCT July 2019
- Treatment of neonate sepsis greatly aided by Vitamin D – RCT June 2019
- Infection in first six months of life: White 69 percent, Black, 78 percent – Jan 2018
- Vitamin D does not help children (if only use 400 IU of D3 or D2 or quarterly) – Cochrane Nov 2016
- Vitamin D improves a child’s immune system – can now be claimed in Europe – Sept 2016
- Rotavirus diarrhea (nearly every child gets it) is strongly associated with low vitamin D – Aug 2015
- Immune System response of infants is associated with higher levels of vitamin D – RCT Nov 2014
- Infant sepsis strongly associated with low vitamin D – Aug 2014
- Middle ear infection (Otitis Media) and Vitamin D – many studies
- Tonsillectomy, tonsollitis and Vitamin D - many studies
- Many infant infections avoided with supplementation with 400 IU of vitamin D – Oct 2012
- TB vaccinations increased vitamin D levels a year later – Jan 2012
Infant-Child category starts with
- No consensus on MINIMUM International Units (IU) for healthy infant of normal weight
- 400 IU Vitamin D is no longer enough
Was OK in the past century, but D levels have been dropping for a great many reasons.
FDA doubles the amount of vitamin D permitted in milk – July 2016 - No consensus: range is 600 to 1600 IU – based on many randomized controlled trials
- Review of 400 IU to 2000 IU daily and higher if non-daily
- Fewer pre-infants were vitamin D deficient when they got 800 IU – RCT Feb 2014
- 1600 IU was the conclusion of three JAMA studies
1000 IU recommended in France and Finland – 2013 - appears to be a good level - 5X less mite allergy after add vitamin D
- Child bone fractures with low vitamin D were 55X more likely to need surgery
- 75 % of SIDS had low vitamin D
- Children stayed in ICU 3.5 days longer if low vitamin D – Dec 2015
- 5 out of 6 children who died in pediatric critical care unit had low vitamin D – May 2014
- Infants have gotten free 400 IU of vitamin D in Turkey since 2005, More for longer would be even better – Feb 2022
- Preemies should have vitamin D supplements – reaching an agreement – April 2021
- Vitamin D loading dose was as effective as daily dosing (rickets in this case) – RCT July 2021
Having a good level of vitamin D cuts in half the amount of:
- Asthma, Chronic illness, Doctor visits, Allergies, infection
Respiratory Tract Infection, Growing pains, Bed wetting
Need even more IUs of vitamin D to get a good level if;
- Have little vitamin D: premie, twin, mother did not get much sun access
- Get little vitamin D: dark skin, little access to sun
- Vitamin D is consumed faster than normal due to sickness
- Older (need at least 100 IU/kilogram, far more if obese)
- Not get any vitamin D from formula (breast fed) or (fortified) milk
Note – formula does not even provide 400 IU of vitamin D daily
Infants-Children need Vitamin D
- Sun is great – well known for 1,000’s of years.
US govt (1934) even said infants should be out in the sun - One country recommended 2,000 IU daily for decades – with no known problems
- As with adults, infants and children can have loading doses and rarely need tests
- Daily dose appears to be best, but monthly seems OK
- Vitamin D is typically given to infants in the form of drops
big difference in taste between brands
can also use water-soluable form of vitamin D in milk, food, juice, - Infants have evolved to get a big boost of vitamin D immediately after birth
Colostrum has 3X more vitamin D than breast milk - provided the mother has any vitamin D to spare - 100 IU per kg of infant July 2011, Poland etc.
More than 100 IU/kg is probably better 854 items in the category Infant/Child See also - 34 pages in VitaminDWiki had BREASTFE*in title as of Jan 2022
- "BIRTH DEFECTS" 172 items as of July 2016
- Stunting OR “low birth weight” OR LBW OR preemie OR preemies OR preterm 1940 items as of Oct 2018
- 153 VitaminDWiki pages contained PRETERM or PREEMIE in title as of Nov 2024
- "SUDDEN INFANT DEATH" OR SIDS 214 items as of Dec 2020
- Overview of Rickets and Vitamin D
- Youth category listing has
175 items along with related searches - Down's syndrome and low vitamin D - several studies
- Rett syndrome associated with low vitamin D, treated by Omega-3
Vitamin D improves a child’s immune system – can now be claimed in Europe – Sept 20165863 visitors, last modified 02 Mar, 2020, This page is in the following categories (# of items in each category)